Por favor, use este identificador para citar o enlazar este ítem:
http://www.repositorio.ufop.br/jspui/handle/123456789/9396
Título : | Continuous post-market sequential safety surveillance with minimum events to signal. |
Autor : | Kulldorff, Martin Silva, Ivair Ramos |
Palabras clave : | Drug safety Surveillance Pharmacovigilance Continuous sequential analysis |
Fecha de publicación : | 2017 |
Citación : | KULLDORFF, M.; SILVA, I. R. Continuous post-market sequential safety surveillance with minimum events to signal. REVSTAT - Statistical Journal, v. 15, p. 373-394, 2017. Disponível em: <https://www.ine.pt/revstat/pdf/REVSTAT_v15-n3-4.pdf>. Acesso em: 16 jan. 2018. |
Resumen : | Continuous sequential analysis is increasingly used for near real-time post-market drug and vaccine safety surveillance. We explore continuous sequential monitoring when the null cannot be rejected until a minimum number of adverse events have occurred. For fixed alpha, one can simultaneously increase the statistical power and reduce the expected time to signal. We also evaluate continuous sequential analysis with a delayed start until a certain sample size has been attained. This is only useful if the start of the surveillance is delayed for logistical reasons. Tables with exact critical values, statistical power and the average times to signal are provided. |
URI : | http://www.repositorio.ufop.br/handle/123456789/9396 |
metadata.dc.identifier.uri2: | https://www.ine.pt/revstat/pdf/REVSTAT_v15-n3-4.pdf |
ISSN : | 1645-6726 |
Aparece en las colecciones: | DEEST - Artigos publicados em periódicos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
ARTIGO_ContinuousPostMarket.pdf Restricted Access | 230,59 kB | Adobe PDF | Visualizar/Abrir |
Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.