Characterization of two isolates of Trypanosoma cruzi obtained from the patient Berenice, the first human case of Chagas disease.
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1996
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Two isolates of Trypanosoma cruzi were obtained
from the patient Berenice, the first human case of
Chagas’ disease (Chagas 1909), when she was 55 and 71
years old, respectively. The isolates were characterized
on the basis of their epimastigote-trypomastigote differentiation
in liquid media and of the electrophoretic pattern
of EcoR1 digestion products of kinetoplast DNA (k-
DNA) minicircles (schizodeme) and isoenzyme patterns
(zymodeme). Clear differences were found between the
isolates, suggesting the occurrence of a heterogeneous
population of T. cruzi in the infection of this patient.
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LANA, M. de et al. Characterization of two isolates of Trypanosoma cruzi obtained from the patient Berenice, the first human case of Chagas disease. Parasitology Research, v. 82, p. 257-260, 1996. Disponível em: <http://link.springer.com/article/10.1007/s004360050106>. Acesso em: 20 jan. 2017.