Applying positive end-expiratory pressure during mechanical ventilation causes pulmonary redox imbalance and inflammation in rats.
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2018
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Mechanical ventilation may induce or aggravate lung injury through the production of
cytokines, inflammatory infiltration of neutrophils and changes in the permeability of the alveolarcapillary
barrier. The use of positive end-expiratory pressure (PEEP) helps improve gas exchanges
avoiding alveolar collapse at the end of expiration. The present study aimed to analyze inflammatory
response and redox imbalance in lungs of rats submitted to mechanical ventilation with and without
positive end-expiratory pressure.
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ANDRADE, M. C. et al. Applying positive end-expiratory pressure during mechanical ventilation causes pulmonary redox imbalance and inflammation in rats. SHOCK, v. 2018, p. 1-24, 2018. Disponível em: <https://insights.ovid.com/pubmed?pmid=29194341>. Acesso em: 05 abr. 2018.