Exploring DNA-interaction and molecular structure of ruthenium/1,2-bis-(diphenylphosphino)ethane)-based complex.
dc.contributor.author | Campideli, Victor Cardoso | |
dc.contributor.author | Montilla Suárez, Jerica Margely | |
dc.contributor.author | Silva, Tiago Almeida | |
dc.contributor.author | Sicupira, Dalila Chaves | |
dc.contributor.author | Oliveira, Katia Mara de | |
dc.contributor.author | Correa, Rodrigo de Souza | |
dc.date.accessioned | 2023-11-22T19:11:01Z | |
dc.date.available | 2023-11-22T19:11:01Z | |
dc.date.issued | 2023 | pt_BR |
dc.description.abstract | The mixture of cis and trans-[RuCl2(dppe)2] (dppe: 1,2-bis-(diphenylphosphino)ethane) was prepared and the interaction with CT-DNA was evaluated by several methods, including UVvis DNA spectroscopic titration, viscosity, and electrochemical studies. Investigation suggests that [RuCl2(dppe)2] interacts moderately with CT-DNA. Interestingly, the cis- and trans-isomers interact differently with DNA, as proved by the square-wave voltammetry studies. Finally, the crystal structure of trans-[RuCl2(dppe)2]Cl was obtained from an electrochemical solution and studied in detail, which presents a distorted octahedral geometry and interatomic parameters different from those found in the trans- [RuCl2(dppe)2] complex. Crystal data for C52H48Cl4P4Ru: triclinic, space group P-1 (no. 2), a = 9.240(3) Å, b = 10.9290(18) Å, c = 11.993(3) Å, α = 78.707(11)°, β = 86.712(13)°, γ = 82.598(13)°, V = 1177.1(5) Å3, Z = 1, T = 293(2) K, μ(MoKα) = 0.732 mm-1, Dcalc = 1.467 g/cm3, 8434 reflections measured (6.934° ≤ 2Θ ≤ 51.986°), 4607 unique (Rint = 0.0973, Rsigma = 0.1171) which were used in all calculations. The final R1 was 0.0537 (I > 2σ(I)) and wR2 was 0.1347 (all data). | pt_BR |
dc.identifier.citation | CAMPIDELI, V. C. et al. Exploring DNA-interaction and molecular structure of ruthenium/1,2-bis-(diphenylphosphino)ethane)-based complex. European Journal of Chemistry, v. 14, p. 193-201, 2023. Disponível em: <https://www.eurjchem.com/index.php/eurjchem/article/view/2402>. Acesso em: 01 ago. 2023. | pt_BR |
dc.identifier.doi | https://doi.org/10.5155/eurjchem.14.2.193-201.2402 | pt_BR |
dc.identifier.issn | 2153-2257 | |
dc.identifier.uri | http://www.repositorio.ufop.br/jspui/handle/123456789/17839 | |
dc.language.iso | en_US | pt_BR |
dc.rights | aberto | pt_BR |
dc.rights.license | This work is published and licensed by Atlanta Publishing House LLC – CC BY NC – Some Rights Reserved. Fonte: PDF do artigo. | pt_BR |
dc.subject | Viscosity | pt_BR |
dc.subject | DNA interaction | pt_BR |
dc.subject | Crystal structure | pt_BR |
dc.subject | Ru/dppe complex | pt_BR |
dc.subject | UV-Vis spectroscopy | pt_BR |
dc.title | Exploring DNA-interaction and molecular structure of ruthenium/1,2-bis-(diphenylphosphino)ethane)-based complex. | pt_BR |
dc.type | Artigo publicado em periodico | pt_BR |
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