Can established cultured papilloma cells harbor bovine papillomavirus?
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Data
2008
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Resumo
Papillomaviruses have been reported to be very dif¬ficult to grow in cell culture. Also, there are no descriptions of cell cultures from lesions of bovine cutaneous papillomatosis, with identification of different bovine papilloma virus (BPV) DNA se¬quences. In the present report, we describe primary cell cultures from samples of cutaneous lesions (warts). We investigated the si¬multaneous presence of different BPV DNA sequences, comparing the original lesion to different passages of the cell cultures and to peripheral blood. BPV 1, 2 and 4 DNA sequences were found in lesion samples, and respective cell cultures and peripheral blood, supporting our previous hypothesis of the possible activity of these sequences in different samples and now also showing how they can be maintained in different passages of cell cultures.
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Bovine papilloma virus, Primary cell cultures, Wart, Cutaneous papillomatosis, Papillomavirus
Citação
CAMPOS, S. R. C. et al. Can established cultured papilloma cells harbor bovine papillomavirus? Genetics and Molecular Research, v. 7, p. 1119-1126, 2008. Disponível em: <http://www.funpecrp.com.br/gmr/year2008/vol7-4/pdf/gmr498.pdf>. Acesso em: 20 ago. 2014.