Synthesis of 4-octyl-2H-1,4-benzo-thiazin-3-ones.
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2003
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Synthesis, physical and analytical properties of 6-alkylacylamino-4-octyl-2H-1,4-benzo-thiazin-3-ones derivatives are described.
These new compounds were prepared by acylation and/or alkylation of the amino group under phase transfer catalysis conditions.
Acid hydrolysis of the alkylacylamino-2H-1,4-benzo-thiazin-3-ones afforded N-alkylamino-benzothiazin-3-ones. Some of these
compounds were evaluated in vitro for possible bacteriostatic activity.
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1,4-Benzothiazines, Antibacterials
Citação
GUARDA, V. L. de M. et al. Synthesis of 4-octyl-2H-1,4-benzo-thiazin-3-ones. European Journal of Medicinal Chemistry, Paris, v. 38, p. 769-793, 2003. Disponível em: <http://www.sciencedirect.com/science/article/pii/S0223523403001272>. Aesso em: 20 jan. 2017.