Metabolic syndrome components can predict C reactive protein concentration in adolescents.

Resumo
Background: Metabolic syndrome (MS) is suggested to be associated with a low grade inflammation state, but the relationship between inflammation biomarkers and the components of metabolic syndrome in adolescents are still lacking. Objective: To investigate the association between Creactive protein (CRP) serum concentrations and metabolic syndrome components in adolescents. Methods: A cross-sectional population based study was conducted. Anthropometric, biochemical and clinical data were collected from 524 adolescents (11-15 years old) randomly sampled from school population of Alegre city, Espírito Santo, Brazil. Data were analyzed by STATA version 9.0. Results: Adolescents with higher values for BMI (p = 0.001) and higher body fat percentage (p = 0.003) had higher CRP concentrations than those with lower BMI and body fat percentage. CRP concentrations was directly correlated with BMI (r = 0.17, p = 0.0001), waist circumference (r = 0.15, p = 0.0005), HDL-c (r = 0.13, p = 0.003), fasting insulin (r = 0.12, p = 0.003) and systolic blood pressure (r = 0.11, p with = 0.01). In the multiple linear regression analysis BMI (r = 0.05, p = 0.002), fasting glucose (r = -0.01, p = 0.003) and HDL-c (r = 0.017, p < 0.001) were associated to CRP concentrations after adjusting for the other components of MS. Conclusion: The association found between individual components of MS and CRP concentrations suggests that inflammation might be an early event in the development of metabolic disorders in adolescents.
Descrição
Palavras-chave
Adolescents, Risk factors, Creactive protein, Síndrome metabólica, Sobrealimentación
Citação
CRUZ, L. L. de et al. Metabolic syndrome components can predict C reactive protein concentration in adolescents. Nutrición Hospitalaria, v. 28, p. 1580-1586, 2013. Disponível em: <http://scielo.isciii.es/scielo.php?pid=S0212-16112013000500032&script=sci_abstract&tlng=en>. Acesso em: 08 nov. 2014.