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Campo Dublin Core | Valor | Idioma |
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dc.contributor.author | Pereira, Michele B. P. | - |
dc.contributor.author | Tisi, Renata | - |
dc.contributor.author | Fietto, Luciano Gomes | - |
dc.contributor.author | Cardoso, Anamaria de Souza | - |
dc.contributor.author | França, Mônica M. | - |
dc.contributor.author | Carvalho, Fernanda Machado de | - |
dc.contributor.author | Trópia, Maria José Magalhães | - |
dc.contributor.author | Martegani, Enzo | - |
dc.contributor.author | Castro, Ieso de Miranda | - |
dc.contributor.author | Brandão, Rogélio Lopes | - |
dc.date.accessioned | 2012-07-18T18:04:35Z | - |
dc.date.available | 2012-07-18T18:04:35Z | - |
dc.date.issued | 2008 | - |
dc.identifier.citation | PEREIRA, M. B. P. et al. Carbonyl cyanidem - chlorophenylhydrazone induced calcium signaling and activation of plasma membrane H1-ATPase in the yeast Saccharomyces cerevisiae. FEMS Yeast Research, v. 8, n.4, p.622-630, jun. 2008. Disponível em: <http://onlinelibrary.wiley.com/doi/10.1111/j.1567-1364.2008.00380.x/pdf>. Acesso em: 18 jul. 2012. | pt_BR |
dc.identifier.issn | 15671364 | - |
dc.identifier.uri | http://www.repositorio.ufop.br/handle/123456789/1164 | - |
dc.description.abstract | The plasma membrane H1-ATPase from Saccharomyces cerevisiae is an enzyme that plays a very important role in the yeast physiology. The addition of protonophores, such as 2,4-dinitrophenol (DNP) and carbonyl cyanide m-chlorophenylhydrazone (CCCP), also triggers a clear in vivo activation of this enzyme. Here, we demonstrate that CCCP-induced activation of the plasma membrane H1-ATPase shares some similarities with the sugar-induced activation of the enzyme. Phospholipase C and protein kinase C activities are essential for this activation process while Gpa2p, a G protein involved in the glucose-induced activation of the ATPase, is not required. CCCP also induces a phospholipase Cdependent increase in intracellular calcium. Moreover, we show that the availability of extracellular calcium is required for CCCP stimulation of H1-ATPase, suggesting a possible connection between calcium signaling and activation of ATPase. | pt_BR |
dc.language.iso | en_US | pt_BR |
dc.subject | Depolarizing compounds | pt_BR |
dc.subject | Saccharomyces cerevisiae | pt_BR |
dc.title | Carbonyl cyanidem - chlorophenylhydrazone induced calcium signaling and activation of plasma membrane H1-ATPase in the yeast Saccharomyces cerevisiae. | pt_BR |
dc.type | Artigo publicado em periodico | pt_BR |
dc.rights.license | O Periódico FEMS Yeast Research concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 500810576. | - |
Aparece nas coleções: | DEFAR - Artigos publicados em periódicos |
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