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Title: Canine visceral leishmaniasis : performance of a rapid diagnostic test (Kalazar Detect TM ) in dogs with and without signs of the disease.
Authors: Lemos, Elenice Moreira
Laurenti, Marcia Dalastra
Moreira, Márcio Antônio Batistela
Reis, Alexandre Barbosa
Giunchetti, Rodolfo Cordeiro
Raychaudhuri, Syamal
Dietze, Reynaldo
Keywords: Canine visceral leishmaniasis
Leishmania chagasi
Rapid test
Issue Date: 2008
Citation: LEMOS, E. M. et al. Canine visceral leishmaniasis : performance of a rapid diagnostic test (Kalazar Detect TM) in dogs with and without signs of the disease. Acta Tropica, v. 107, p. 205-207, 2008. Disponível em: <>. Acesso em: 05 jul. 2012.
Abstract: Current visceral leishmaniasis (VL) control programs in Brazil include the infected dog elimination but, despite this strategy, the incidence of human VL is still increasing. One of the reasons is the long delay between sample collection, analysis, control implementation and the low sensitivity of diagnostic tests. Due to the high prevalence of asymptomatic dogs, the diagnosis of these animals is important considering their vector infection capacity. Hence, a rapid and accurate diagnosis of canine visceral leishmaniasis is essential for an efficient surveillance program. In this study we evaluated the performance of rK39 antigen in an immunochromatographic format to detect symptomatic and asymptomatic Leishmania chagasi infection in dogs and compared the results with those using a crude antigen ELISA. The sensitivity of rK39 dipstick and ELISA were 83% vs. 95%, respectively, while the specificity was both 100%. Our results also demonstrated that the dipstick test was able to detect infected dogs presenting different clinical forms.
ISSN: 0001706X
metadata.dc.rights.license: O periódico Acta Tropica concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3291401361436.
Appears in Collections:DEACL - Artigos publicados em periódicos

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