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dc.contributor.authorSilva, Elisângela F.-
dc.contributor.authorOrsi, Mariana-
dc.contributor.authorAndrade, Ângela Leão-
dc.contributor.authorDomingues, Rosana Zacarias-
dc.contributor.authorSilva, Breno de Mello-
dc.contributor.authorAraújo, Helena Rocha Corrêa de-
dc.contributor.authorPimenta, Paulo Filemon Paolucci-
dc.contributor.authorDiamond, Michael S.-
dc.contributor.authorRocha, Eliseu S. O.-
dc.contributor.authorKroon, Erna Geessien-
dc.contributor.authorMalaquias, Luiz Cosme Cotta-
dc.contributor.authorCoelho, Luiz Felipe Leomil-
dc.date.accessioned2017-03-16T13:34:41Z-
dc.date.available2017-03-16T13:34:41Z-
dc.date.issued2012-
dc.identifier.citationSILVA, E. F. et al. A tetravalent dengue nanoparticle stimulates antibody production in mice. Journal of Nanobiotechnology, v. 10, p. 13, 2012. Disponível em: <https://jnanobiotechnology.biomedcentral.com/articles/10.1186/1477-3155-10-13> Acesso em: 19 fev. 2017.pt_BR
dc.identifier.issn1477-3155-
dc.identifier.urihttp://www.repositorio.ufop.br/handle/123456789/7383-
dc.description.abstractDengue is a major public health problem worldwide, especially in the tropical and subtropical regions of the world. Infection with a single Dengue virus (DENV) serotype causes a mild, self-limiting febrile illness called dengue fever. However, a subset of patients experiencing secondary infection with a different serotype progresses to the severe form of the disease, dengue hemorrhagic fever/dengue shock syndrome. Currently, there are no licensed vaccines or antiviral drugs to prevent or treat dengue infections. Biodegradable nanoparticles coated with proteins represent a promising method for in vivo delivery of vaccines.pt_BR
dc.language.isopt_BRpt_BR
dc.rightsabertopt_BR
dc.subjectInactivated Dengue víruspt_BR
dc.subjectNanoparticlespt_BR
dc.subjectHumoral responsept_BR
dc.titleA tetravalent dengue nanoparticle stimulates antibody production in mice.pt_BR
dc.typeArtigo publicado em periodicopt_BR
dc.rights.licenseThis is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Fonte: o próprio artigo.pt_BR
dc.identifier.doihttps://doi.org/10.1186/1477-3155-10-13-
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