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Título: | Differential expression of cocaine- and amphetamine-regulated transcript-immunoreactivity in the rat spinal preganglionic nuclei. |
Autor(es): | Dun, S. L. Chianca Júnior, Deoclécio Alves Dun, Nae J. Yang, J. Chang, Jaw-Kang |
Palavras-chave: | Neurons Spinal cord Cell column |
Data do documento: | 2000 |
Referência: | DUN, S. L. et al. Differential expression of cocaine- and amphetamine-regulated transcript-immunoreactivity in the rat spinal preganglionic nuclei. Neuroscience Letters. Supplement, USA, v. 294, n.3, p. 143-146, 2000. Disponível em: <http://www.sciencedirect.com/science/article/pii/S0304394000015755>. Acesso em: 08 nov. 2014. |
Resumo: | The distribution of cocaine- and amphetamine-regulated transcript-like immunoreactivity (CART-LI) was investigated in the rat spinal cords with the use of an antiserum against the CART peptide fragment 55±102. CART-LI ®bers were concentrated in the super®cial layers of the dorsal horn of all segments. In addition to CART-LI ®bers, intensely labeled somata were detected in the intermediolateral cell column (IML) and other sympathetic preganglionic nuclei of the thoracolumbar segments. In the lumbosacral segments, CART-LI ®bers but not somata were seen in the sacral parasympathetic nucleus. Double-labeling the spinal sections with choline acetyltransferase (ChAT)-antisera and CARTantisera revealed that the large majority of ChAT-positive somata in the sympathetic preganglionic nuclei were CARTpositive, whereas ChAT-positive somata in the parasympathetic preganglionic nuclei were CART-negative. Our results show that CART-LI is selectively expressed in a population of sympathetic preganglionic neurons (SPNs), but not in parasympathetic preganglionic neurons (PPNs) of the rat. |
URI: | http://www.repositorio.ufop.br/handle/123456789/4283 |
DOI: | https://doi.org/10.1016/S0304-3940(00)01575-5 |
ISSN: | 0304-3940 |
Licença: | O periódico Neuroscience Letters concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3521411315026. |
Aparece nas coleções: | DECBI - Artigos publicados em periódicos |
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Arquivo | Descrição | Tamanho | Formato | |
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ARTIGO_DifferentialexpressionCocaine.pdf | 542,64 kB | Adobe PDF | Visualizar/Abrir |
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