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Title: Synthesis of 4-octyl-2H-1,4-benzo-thiazin-3-ones.
Authors: Guarda, Vera Lúcia de Miranda
Perrissin, Monique
Thomasson, François
Ximenes, Eulália Camelo Pessoa de Azevedo
Galdino, Suely Lins
Pitta, Ivan da Rocha
Luu-Duc, Cuong
Barbe, Jacques
Keywords: 1,4-Benzothiazines
Issue Date: 2003
Citation: GUARDA, V. L. de M. et al. Synthesis of 4-octyl-2H-1,4-benzo-thiazin-3-ones. European Journal of Medicinal Chemistry, Paris, v. 38, p. 769-793, 2003. Disponível em: <>. Aesso em: 20 jan. 2017.
Abstract: Synthesis, physical and analytical properties of 6-alkylacylamino-4-octyl-2H-1,4-benzo-thiazin-3-ones derivatives are described. These new compounds were prepared by acylation and/or alkylation of the amino group under phase transfer catalysis conditions. Acid hydrolysis of the alkylacylamino-2H-1,4-benzo-thiazin-3-ones afforded N-alkylamino-benzothiazin-3-ones. Some of these compounds were evaluated in vitro for possible bacteriostatic activity.
ISSN: 0223-5234
Appears in Collections:DEFAR - Artigos publicados em periódicos

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