Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorMagalhães, Cássia Gonçalves-
dc.contributor.authorSilva, Grácia Divina de Fátima-
dc.contributor.authorMoujir, Laila-
dc.contributor.authorLópez, Manuel R.-
dc.contributor.authorFigueiredo, Rute Cunha-
dc.contributor.authorVieira Filho, Sidney Augusto-
dc.identifier.citationMAGALHÃES, C. G. et al. Salicassin, an unprecedented chalcone diterpene adduct and a quinone methide triterpenoid from Maytenus salicifolia. Helvetica Chimica Acta, v. 96, p. 1046-1054, 2013. Disponível em: <>. Acesso em: 20 mai. 2017.pt_BR
dc.description.abstractIn continuation of our work on Maytenus salicifolia, we report herein the isolation and structuralelucidation of two new compounds, salicassin (1), a diterpene-chalcone adduct with an unprecedented C-framework, and (16b)-16-hydroxypristimerin (2), a quinone methide triterpenoid. Their structures wereelucidated on the basis of spectroscopic analysis, including 1D- and 2D-NMR techniques (COSY,ROESY, HSQC, and HMBC). In addition, 22 known compounds were isolated and characterized bycomparison of their spectra with reported data. Compound 2, structurally related to the well knowncytotoxic quinone methide triterpenoids, exhibited an antiproliferative effect on HeLa, A-549, and HL-60 human cell lines, with IC50values of 2.2, 3.2, and 2.7 mm, respectively.pt_BR
dc.titleSalicassin, an unprecedented chalcone diterpene adduct and a quinone methide triterpenoid from Maytenus salicifolia.pt_BR
dc.typeArtigo publicado em periodicopt_BR
Appears in Collections:DEQUI - Artigos publicados em periódicos

Files in This Item:
File Description SizeFormat 
  Restricted Access
223,85 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.