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http://www.repositorio.ufop.br/jspui/handle/123456789/15945
Título: | Cost analysis of smear microscopy and the Xpert assay for tuberculosis diagnosis : average turnaround time. |
Autor(es): | Figueredo, Lida Jouca de Assis Miranda, Silvana Spíndola de Santos, Lucas Benício dos Manso, Caroline Gontijo Gonçalves Soares, Valéria Martins Alves, Suely Vater, Maria Cláudia Kritski, Afrânio Lineu Carvalho, Wânia da Silva Pádua, Cristiane Menezes de Almeida, Isabela Neves de |
Palavras-chave: | Mycobacterium tuberculosis Molecular diagnostic Pulmonary tuberculosis Health system |
Data do documento: | 2020 |
Referência: | FIGUEREDO, L. J. de A. at al. Cost analysis of smear microscopy and the Xpert assay for tuberculosis diagnosis: average turnaround time. Sociedade Brasileira de Medicina Tropical, v. 53, 2020. Disponível em: <https://www.scielo.br/j/rsbmt/a/QVfJCfTHD3KBYK3TRPbK4Gd/citation/?lang=en>. Acesso em: 11 out. 2022. |
Resumo: | Introduction: Rapid and accurate tuberculosis detection is critical for improving patient diagnosis and decreasing tuberculosis transmission. Molecular assays can significantly increase laboratory costs; therefore, the average time and economic impact should be evaluated before implementing a new technology. The aim of this study was to evaluate the cost and average turnaround time of smear microscopy and Xpert assay at a university hospital. Methods: The turnaround time and cost of the laboratory diagnosis of tuberculosis were calculated based on the mean cost and activity based costing (ABC). Results: The average turnaround time for smear microscopy was 16.6 hours while that for Xpert was 24.1 hours. The Xpert had a mean cost of USD 17.37 with an ABC of USD 10.86, while smear microscopy had a mean cost of USD 13.31 with an ABC of USD 6.01. The sensitivity of smear microscopy was 42.9% and its specificity was 99.1%, while the Xpert assay had a sensitivity of 100% and a specificity of 96.7%. Conclusions: The Xpert assay has high accuracy; however, the turnaround time and cost of smear microscopy were lower than those of Xpert. |
URI: | http://www.repositorio.ufop.br/jspui/handle/123456789/15945 |
DOI: | https://doi.org/10.1590/0037-8682-0314-2020 |
ISSN: | 1678-9849 |
Licença: | This is an open access article distributed under the terms of the Creative Commons license. Fonte: o PDF do artigo. |
Aparece nas coleções: | DEACL - Artigos publicados em periódicos |
Arquivos associados a este item:
Arquivo | Descrição | Tamanho | Formato | |
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ARTIGO_CostAnalysisSmear.pdf | 1,06 MB | Adobe PDF | Visualizar/Abrir |
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