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Title: Impact of clinical, sociodemographic and quality of life factors on dialysis patient survival : a nine-year follow-up cohort study.
Other Titles: Impacto de fatores clínicos, sociodemográficos e de qualidade de vida na sobrevida de pacientes em diálise : um estudo de coorte com nove anos de seguimento.
Authors: Brito, Daniela Cristina Sampaio de
Machado, Elaine Leandro
Reis, Ilka Afonso
Cherchiglia, Mariângela Leal
Keywords: Chronic kidney failure
Renal replacement therapy
Issue Date: 2020
Citation: BRITO, D. C. S. de et al. Impact of clinical, sociodemographic and quality of life factors on dialysis patient survival: a nine-year follow-up cohort study. Cadernos de Saúde Pública, v. 36, n. 12, 2020. Disponível em: <>. Acesso em: 10 jun. 2021.
Abstract: Although renal replacement therapy has contributed to the survival of chronic kidney failure (CKF) patients, mortality remains a major concern. This study aimed to identify the factors associated with mortality in a prospective cohort of CKF patients. Sociodemographic, clinical, nutritional, lifestyle and quality of life data were collected from 712 patients. The instruments used were the Short-Form Health Survey (SF-36), Global Subjective Assessment (GSA) and Charlson Comorbidity Index (CCI) questionnaires. A total of 444 patients died during the study. After five years of follow-up, factors such as not being married (hazard ratio – HR = 1.289, 95%CI: 1.001; 1.660), a low frequency of leisure activities (HR = 1.321; 95%CI: 1.010; 1.727) and not be ing transplanted (HR = 7.246; 95%CI: 3.359; 15.630) remained independently associated with the risk of mortality. At the end of the follow-up period, factors such as not being married (HR = 1.337, 95%CI: 1.019; 1.756), not being transplanted (HR = 7.341, 95%CI: 3.829; 14.075) and having a worse nutritional status (HR = 1.363, 95%CI: 1.002; 1.853) remained independently associated with an increased risk of mortality, whereas a high schooling level (10 to 12 years, HR = 0.578, 95%CI: 0.344; 0.972; and over 12 years, HR = 0.561, 95%CI: 0.329; 0.956) and a better SF-36 physical functioning score (HR = 0.992, 95%CI: 0.987; 0.998) were protective factors associated with survival. The survival of patients with CKF is associated with factors not restricted to the clinical spectrum. The following factors were associated with high mortality: not being married, low schooling level, a limited social routine, a longer time on dialysis, worse nutritional status, and worse physical functioning.
ISSN: 1678-4464
metadata.dc.rights.license: This article is published in Open Access under the Creative Commons Attribution license, which allows use, distribution, and reproduction in any medium, without restrictions, as long as the original work is correctly cited. Fonte: o PDF do artigo.
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