Please use this identifier to cite or link to this item:
Title: Salt-dependent hypertension and inflammation : targeting the gut-brain axis and the immune system with Brazilian green propolis.
Authors: Batista, Marcos Adriano Carlos
Braga, Daiane Cristina de Assis
Moura, Sandra Aparecida Lima de
Souza, Gustavo Henrique Bianco de
Santos, Orlando David Henrique dos
Cardoso, Leonardo Máximo
Keywords: Sodium
Sympathetic drive
Issue Date: 2020
Citation: BATISTA, M. A. C. et al. Salt-dependent hypertension and inflammation: targeting the gut-brain axis and the immune system with Brazilian green propolis. Inflammopharmacology, v. 28, p. 1163-1182, 2020. Disponível em: <>. Acesso em: 10 jun. 2021.
Abstract: Systemic arterial hypertension (SAH) is a major health problem around the world and its development has been associated with exceeding salt consumption by the modern society. The mechanisms by which salt consumption increase blood pressure (BP) involve several homeostatic systems but many details have not yet been fully elucidated. Evidences accumulated over the last 60 decades raised the involvement of the immune system in the hypertension development and opened a range of possibilities for new therapeutic targets. Green propolis is a promising natural product with potent anti-infammatory properties acting on specifc targets, most of them participating in the gut–brain axis of the sodium-dependent hypertension. New anti-hypertensive products reinforce the therapeutic arsenal improving the corollary of choices, especially in those cases where patients are resistant or refractory to conventional therapy. This review sought to bring the newest advances in the feld articulating evidences that show a cross-talking between infammation and the central mechanisms involved with the sodium-dependent hypertension as well as the stablished actions of green propolis and some of its biologically active compounds on the immune cells and cytokines that would be involved with its anti-hypertensive properties.
ISSN: 1568-5608
Appears in Collections:DECBI - Artigos publicados em periódicos

Files in This Item:
File Description SizeFormat 
  Restricted Access
2,44 MBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.