DSpace Coleção:http://www.repositorio.ufop.br/jspui/handle/123456789/5712024-03-28T22:07:44Z2024-03-28T22:07:44ZHeart rate variability : from recording precautions to applicability to physical exercise.Souza, Perciliany Martins deAraújo, Cássia Regina VieiraMocaiber, IzabelaNorte, Carlos EduardoBecker, Lenice KappesSouza, Gabriela Guerra Leal dehttp://www.repositorio.ufop.br/jspui/handle/123456789/180332024-01-24T20:15:36Z2022-01-01T00:00:00ZTítulo: Heart rate variability : from recording precautions to applicability to physical exercise.
Autor(es): Souza, Perciliany Martins de; Araújo, Cássia Regina Vieira; Mocaiber, Izabela; Norte, Carlos Eduardo; Becker, Lenice Kappes; Souza, Gabriela Guerra Leal de
Resumo: Aim: This narrative review sought to address heart rate variability (HRV) based on concepts and definitions, methods of recording and processing signals, signal interpretation, influencing factors, and applicability to physical exercise. Methods: Bibliographic survey of works published between 2000 and 2022 in
PubMed, Scopus, Web of Science, Scielo databases. Results: HRV is a non-invasive method for measuring
the action of the autonomic nervous system in the heart and has been used as a marker of physical and
mental health. HRV measurements can be performed by recording an electrocardiogram or frequency
meter, which allows the extraction of several HRV parameters using linear and non-linear methods. Conclusion: HRV is a variable that can be influenced by several factors, and its role can be explained based on
four theories. Physical training can be used as a marker of exercise intensity control.2022-01-01T00:00:00ZMetabolomic and elemental profiling of blood serum in bladder cancer.Ossoliński, KrzysztofRuman, TomaszCopié, ValérieTripet, Brian P.Nogueira, Leonardo BrandãoNogueira, Katiane de Oliveira Pinto CoelhoKołodziej, ArturAltamer, Aneta PłazaOssolinska, AnnaOssolinski, TadeuszNizioł, Joannahttp://www.repositorio.ufop.br/jspui/handle/123456789/179692023-12-20T20:10:49Z2022-01-01T00:00:00ZTítulo: Metabolomic and elemental profiling of blood serum in bladder cancer.
Autor(es): Ossoliński, Krzysztof; Ruman, Tomasz; Copié, Valérie; Tripet, Brian P.; Nogueira, Leonardo Brandão; Nogueira, Katiane de Oliveira Pinto Coelho; Kołodziej, Artur; Altamer, Aneta Płaza; Ossolinska, Anna; Ossolinski, Tadeusz; Nizioł, Joanna
Resumo: Bladder cancer (BC) is one of the most frequently diagnosed types of urinary cancer. Despite advances in
treatment methods, no specific biomarkers are currently in use. Targeted and untargeted profiling of
metabolites and elements of human blood serum from 100 BC patients and the same number of normal
controls (NCs), with external validation, was attempted using three analytical methods, i.e., nuclear
magnetic resonance, gold and silver-109 nanoparticle-based laser desorption/ionization mass spectrometry (LDI-MS), and inductively coupled plasma optical emission spectrometry (ICP-OES). All results
were subjected to multivariate statistical analysis. Four potential serum biomarkers of BC, namely, isobutyrate, pyroglutamate, choline, and acetate, were quantified with proton nuclear magnetic resonance,
which had excellent predictive ability as judged by the area under the curve (AUC) value of 0.999. Two
elements, Li and Fe, were also found to distinguish between cancer and control samples, as judged from
ICP-OES data and AUC of 0.807 (in validation set). Twenty-five putatively identified compounds, mostly
related to glycans and lipids, differentiated BC from NCs, as detected using LDI-MS. Five serum metabolites were found to discriminate between tumor grades and nine metabolites between tumor stages.
The results from three different analytical platforms demonstrate that the identified distinct serum
metabolites and metal elements have potential to be used for noninvasive detection, staging, and grading
of BC.2022-01-01T00:00:00ZNew insights into plant natriuretic peptide evolution : from the lysogenic conversion in Xanthomonas to the lateral transfer to the whitefly Bemisia tabaci.Patané, José Salvatore LeisterMoreira, Leandro MarcioTeixeira, Marcus de MeloMartins Junior, JoaquimSetubal, João CarlosVarani, Alessandro de Mellohttp://www.repositorio.ufop.br/jspui/handle/123456789/179682023-12-20T20:01:58Z2022-01-01T00:00:00ZTítulo: New insights into plant natriuretic peptide evolution : from the lysogenic conversion in Xanthomonas to the lateral transfer to the whitefly Bemisia tabaci.
Autor(es): Patané, José Salvatore Leister; Moreira, Leandro Marcio; Teixeira, Marcus de Melo; Martins Junior, Joaquim; Setubal, João Carlos; Varani, Alessandro de Mello
Resumo: Plant natriuretic peptide-like (PNP) are signaling molecules related to adaptive responses to stress. The Arabidopsis thaliana PNP (AtPNP-A) is capable of modulating catalase 2 (CAT2) and rubisco activase (RCA) activity in
some circumstances. Interestingly, many plant-pathogens co-opted PNP-like molecules to their benefit. For
instance, the citrus pathogen Xanthomonas citri carries a PNP-like (XacPNP) that can mimic and regulate plant
homeostasis, and many phytopathogenic fungi carry effectors (e.g., Ave1 and AvrLm6) that are indeed PNP-like
homologs. This work investigates the PNP-like evolution across the tree of life, revealing many parallel gains and
duplications in plant and fungi kingdoms. All PNP-like proteins in the final dataset are structurally similar,
containing the AtPNP-A active domains modulating CAT2 activity and RCA interaction. Comparative genomics
evinced that XacPNP is a lysogenic conversion factor associated with a Myoviridae-like prophage identified in
many Xanthomonas species. Surprisingly, a PNP-like homolog was identified in Bemisia tabaci, an important
agricultural pest, being to date the second example of lateral gene transfer (LGT) from plant to the whitefly.
Moreover, the Bemisia PNP-like homolog can also be considered a potential new effector of this phloem-feeding
insect. Noteworthy, the whiteflies infest many plants carrying PNP-like copies and interact with some of their
bacterial and fungal pathogens, strongly suggesting complex recipient/donor traits of PNP by LGT and bringing
new insights into the evolution of host-pathogen arms race across the tree of life.2022-01-01T00:00:00ZCardiac changes in spontaneously hypertensive rats : modulation by aerobic exercise.Teles, Maria CecíliaPortes, Alexandre Martins OliveiraCoelho, Bianca Iara CamposResende, Letícia TeresinhaIsoldi, Mauro Césarhttp://www.repositorio.ufop.br/jspui/handle/123456789/179672023-12-20T19:57:00Z2023-01-01T00:00:00ZTítulo: Cardiac changes in spontaneously hypertensive rats : modulation by aerobic exercise.
Autor(es): Teles, Maria Cecília; Portes, Alexandre Martins Oliveira; Coelho, Bianca Iara Campos; Resende, Letícia Teresinha; Isoldi, Mauro César
Resumo: Systemic arterial hypertension is a multifactorial clinical condition characterized by high and sustained levels of
blood pressure. For a better understanding of the pathophysiology of hypertension, studies are conducted with
spontaneously hypertensive animals, which allow the investigation of physiological changes that in most cases
cannot be studied in humans. In these animals, myocardial remodeling, increased pro-inflammatory markers,
redox imbalance and contractile dysfunctions that lead to changes in cardiac function can be observed. However,
it can be inferring that aerobic training improves cardiac function and cardiomyocyte contractility, in addition to
controlling inflammation and reducing oxidative stress in cardiac muscle, despite this, the precise mechanisms by
which physical exercise improves cardiovascular control are not fully understood. In this review, we provide an
overview of the pathophysiological changes that affect the heart of spontaneously hypertensive animals and their
modulation by aerobic exercise.2023-01-01T00:00:00Z